16th International Course on Dengue, Zika and other Emergent Arboviruses 12-23 August 2019


12 – 23 August 2019
Institute of Tropical Medicine “Pedro Kourí”, Havana, Cuba

Second Announcement

Under the auspices of:

Institute of Tropical Medicine “Pedro Kourí” (IPK)
Cuban Society of Microbiology and Parasitology (SCMP)
Cuban Ministry of Public Health (MINSAP)
Pan American Health Organization/ World Health Organization (PAHO/WHO)
Fundación Mundo Sano
Institute of Tropical Medicine, Amberes, Belgium
Neglected Tropical Disease Program, WHO
Academia de Ciencias de Cuba, ACC
Latin American Association of Immunology, ALAI
Centro de Ingeniería Genética y Biotecnología, CIGB
American Society of Microbiology, ASM
American Society of Tropical Medicine and Hygiene, ASTMH

Aedes aegypti and Aedes albopictus geographical expansion preceded dengue emergence due to the impact of increasing urbanization of the human population and climatic, social and environmental changes. These conditions not only favored dengue expansion but also the emergence of chikungunya and Zika, as well as the re-emergence of yellow fever. The co-circulation of these arboviruses poses new challenges to global public health.

The PAHO/WHO Collaborating Center for the Study of Dengue and its Control of the Institute of Tropical Medicine “Pedro Kourí”/MINSAP, the Cuban Society of Microbiology and Parasitology, the Cuban Ministry of Public Health and PAHO/WHO announce the 16th International Course on Dengue, Zika and Other Emergent Arboviruses to be held on 12 – 23 August 2019. This activity is organized in the framework of the 500th Anniversary of the ¨Villa San Cristobal de la Habana¨.

During the two-week course, the regional and global epidemiological situation of important arboviruses will be updated. A prestigious faculty of professors from across the globe will present sessions and discussions on clinical management; vector control; scientific advances in pathogenesis, vaccines and antiviral development; new vector control tools; the influence of host genetics as well as the genetics of the vector and the viruses; emergency control; new international initiatives for arbovirus control and prevention; among other interesting and important topics.


That medical doctors, virologists, immunologists, social scientists, epidemiologists and entomologists, among others, receive the latest scientific information and have an opportunity to discuss relevant topics on dengue, Zika, chikungunya, and the situation of arboviruses in general.


The following topics will be covered through lectures, roundtable discussions, seminars, topic-specific symposia, and practical activities:
• Global situation: Dengue, Zika, Chikungunya and Yellow fever
• Situation in the Region of the Americas: Dengue, Zika, Chikungunya and Yellow fever – Where are we today?
• Current and future challenges: International initiatives
• Integrated Management Strategy for Arboviral Diseases
• Integrated surveillance
• Integrated Vector Management
• Clinical picture and pathology. Case definitions. Differential diagnosis. Clinical management
• Genome and viral structure. Replication and viral evolution (flavivirus, alphavirus)
• Zika in pregnant woman
• Zika sexual transmission
• Neurological disorders associated with dengue, Zika and chikungunya
• Chronic chikungunya: What do we know?
• Serological and molecular diagnostics. Challenges of laboratory surveillance for arboviruses
• Immune response
• Host genetic factors and dengue and Zika severity
• Pathogenesis. Role of immune-enhancement in dengue and Zika
• Flavivirus NS1 protein
• Vaccine and antiviral advances
Aedes aegypti ecology. Vector competence
• Vector dynamics in arbovirus transmission
• Chemical and biological methods for vector control
• New tools and strategies for vector control
• Sterile insect technique: Experiences in the Region of the Americas
• Mechanisms of insecticide resistance
• Virus-mosquito interaction
• Social and community aspects of arbovirus transmission and control
• Mathematical models for transmission of dengue and other arboviruses study. Prediction models
• Ecobiosocial approach for arbovirus control and prevention
• Role of the community in vector control
• Health economics and control of Aedes aegypti transmitted diseases
• Planning for emergency situations
• Climate change and transmission of arboviruses
• Research priorities


Kevin Arien, Institute of Tropical Medicine, Belgium
Mabel Carabali, McGill University, Canada
Chong Chee Seng, NEA, Singapore
Kyung Choi, UTMB, USA
Alex Cook, NUS, Singapore
Delia Enria, Argentina
Manuel Espinosa, Fundación Mundo Sano
Florence Fouquet, TDR-WHO
Leticia Franco, PAHO/OMS
Mariano A. Garcia-Blanco, UTMB, USA
Scott Halstead, DVI
Eva Harris, University of California in  Berkeley, USA
Nildimar Honorio, Instituto FioCruz, Brazil
Olaff  Horstick, Heidelberg University, Germany
Xavier de Lamballerie, Aix-Marseille University, France
Linda Lloyd, USA
Felipe Lorenzato, Takeda
Kleber Luz, Universidad Federal Rio Grande Du Norte, Brazil
Jairo Méndez, PAHO/WHO
José Moya, PAHO, Cuba
Jorge L. Muñoz-Jordán, CDC, Puerto Rico
Jorge Osorio, Universidad Wisconsin, USA
Christopher Oxenford, WHO
Carlos Pardo, Johns Hopkins University School of Medicine, USA
Ernesto Pleites, Hospital Bloom, El Salvador
Amadou Alpha SALL, Instituto Pasteur, Senegal
Aravinda de Silva, University of North Carolina, USA
Fabrice Simon, Laveran Military Teaching Hospital, France
Jiaren Sun, UTMB, USA
S. Thangamani,  UTMB, USA
Patrick Van der Stuyft, Gent University, Belgium
VeerleVanlerbergue, Institute of Tropical Medicine, Belgium
Xaveer Van Ostade, University of Antwerp, Belgium
Wim Vanden Berghe, University of Antwerp, Belgium
Nikos Vasilakis, UTMB, USA
Gonzalo M. Vazquez-Prokopec, Emory University, USA
Anubis Vega, Instituto Pasteur, Guadaloupe
RamanVelayudhan, NTDP, WHO
Tian Wang, UTMB, USA
Scott Weaver, UTMB, USA
Ping Wu, UTMB, USA


María G. Guzmán, Eric Martínez, María E. Toledo, Juan Bisset, Susana Vázquez, Virginia Capó, Mayling Alvarez, Ana B. Pérez, Beatriz Sierra, Pedro Ariel Martínez, Rosa Ramírez, Didye Ruiz, Daniel González, Omar Fuentes, Magdalena Rodríguez, Alberto Baly, Maria del C. Marquetti, Dennis Pérez, Martha Castro, Osvaldo Castro, José L Pelegrino, Pedro Más, Domingo Montada, Francisco Duran, Carilda Peña, Maritza Pupo, Lázaro Gil, Alicia Reyes, Manuel Romero, among other prestigious professors and collaborators from IPK, the Center for Genetic Engineering and Biotechnology (CIGB), the University of Havana and the Ministry of Public Health.


The Course is structured in a theoretical section (Week 1, 12 – 16 August) and a practical section (Week 2, 19 – 23 August).

The theoretical section includes general lectures, roundtable discussions and topic-specific symposia.

During the practical section, participants will select one of five groups according to their interests: clinical care, entomology and vector control, virology/immunology, epidemiology, and community participation.

Practical courses (19-23 August)

Epidemiology: This workshop will include a Course on modeling the dynamic of dengue (and other flaviviruses) transmission considering the complexities of the host immunity, the virus serotype co-circulation and the vector among other factors. The models and EWARS developed by WHO/TDR, NEA/Singapore, Instituto de Meteorología/Cuba will be shown. The workshop will also give an introduction on the Cost Effectiveness estimations of the interventions against flaviviruses/arboviruses and vector control (IPK/Cuba). The  System for the automatic classification of high risk areas of arbovirus transmission (University of Villa Clara/Cuba) will be presented.

Virology-immunology: Molecular diagnosis of dengue, zika, chikungunya and Yellow fever will be updated as well as the serological diagnostic of flaviviruses and its challenges. The applications of nucleotidic sequence and NGS for the genetic characterization of isolates will be presented. Expression of activation markers of human monocytes for flavivirus pathogenesis research. Virus detection in mosquitoes

Clinic-pathology: Clinic of dengue, zika and chikungunya. Case presentation. Differential diagnosis. Warning signs for dengue.  Pathology of dengue. Flavivirus infections in pregnant women. Chronic chikungunya.

Entomology-vector control: Identification of bacteria entomopathogens for the quality control of biolarvicides, Detinova technique (to determine the physiologic age of Aedes aegypti, of importance related directly to dengue transmission and effectivity of vector control methods),  Aedes vector competence determination for dengue viruses, insecticide resistance of  Ae. aegypti. MALDI-TOF for the identification of mosquito species.

Social determinants: e will address methodological aspects to approach social determinants within prevention and control strategies for dengue and other arboviruses. Practical examples of procedures and instruments employed for monitoring and evaluation of social determinants will be provided; as well as planning, organization and evaluation tools to address social determinants with community participation.

Poster session: Participants will have the opportunity to present their projects in a poster session during Week 1. Poster characteristics: 94cm wide X 140cm high (vertical position). Deadline for abstract submission: July 1, 2019. For further information contact Dr. Martha Castro, martac@ipk.sld.cu

Concurrent sessions: Within the framework of the 16th International Course of Dengue, Zika and Emerging Arbovirus, between August 19 and 21, the 5th Annual Meeting of the Dentarget Network (Effectiveness of targeted, risk assessment based, dengue control, for its acronym in English) will be held at the Institute of Tropical Medicine ¨Pedro Kouri¨, Havana, Cuba. Researchers from Brazil, Mexico, EU, Colombia, Belgium and Cuba will participate in that meeting with the explicit objective of continuing cooperation among different countries in Latin America and Europe, with as subject  the development of research on  evaluating alternative strategies for the prevention and control of arbovirosis based on risk assessment. The results of joint projects, which are conducted since its establishment in 2014, will be presented and discussed in this direction.

Other concurrent meetings will be announce in due time.


The official languages of the Course: Spanish and English. Translation in both languages will be available during the theoretical section (Week 1).

REGISTRATION: Theoretical and Practical Sections = $ 800.00 CUC
• Includes registration for both the theoretical and practical sections (Weeks 1 and 2), course materials, welcome cocktail and farewell dinner.
• Participants may attend either the theoretical or the practical section, or both sections.
• Registration fee for the theoretical section only (Week 1): 12 – 16 August 2019 = $ 500.00CUC
Registration fee for the practical section only (Week 2): 19 – 23 August 2019 = $ 400.00 CUC
• Those interested should submit the registration form to lupe@ipk.sld.cu

Registration deadline: 20 July 2019

Download Registration form imagen icono de descarga(80 congreso)

Hotel booking information

Fees payment  information

For further information please contact:

Prof. María G. Guzmán, MD, PhD
Head, Center for Research, Diagnosis and Reference (CIDR)
Institute of Tropical Medicine “Pedro Kourí” (IPK)
Director, WHO/PAHO Collaborating Center for Dengue and its Control
Telephone: +53 7 255-3556
Fax: +53 7 204-6051
Email: lupe@ipk.sld.cu