13th International Dengue Course

Under the auspices of

“Pedro Kourí” Tropical Medicine Institute (IPK)
Cuban Society of Microbiology & Parasitology
Consejo Nacional de Sociedades Científicas de la Salud (CNSCS)
Ministry of Public Health of the Republic of Cuba (MINSAP)
Pan American Health Organization (PAHO)/ World Health Organization (WHO)
Regional Dengue Program, PAHO
WHO Special Program for Research and Training in Tropical Diseases (TDR/WHO)
Initiative for Vaccine Research (IVR/WHO)
Neglected Tropical Diseases (NTD/WHO)
European Society of Clinical Micribiology and Infectious Diseases (ESCMID)
IDAM
DENFREE
Fundación Mundo Sano

An increase in dengue transmission has been observed in the last 40 years with its expansion to other geographical areas, the increasing in the report of epidemics and dengue cases including severe and fatal cases. Recently the World Heath Organization, WHO, introduced a new dengue clinical classification (dengue and severe dengue) that is under implementation in endemic countries. Besides, WHO Global strategy for dengue prevention and control for the period 2012-2020 was published with the aim to diminishing the mortality by 50% and morbidity by 25% in this period.

In this context, the PAHO/WHO Collaborating Center for the Study of Dengue and its Vector of the “Pedro Kourí’’ Tropical Medicine Institute (IPK), Havana, Cuba, together with the Cuban Ministry of Public Health, the Cuban Society of Microbiology & Parasitology, the Pan American Health Organization (PAHO) among others will organize the 13th edition of the dengue international course at the “Pedro Kouri” Tropical Medicine Institute of Havana, from 12-23 August 2013.

OBJECTIVE OF THE COURSE
The Course’s objective is that participants – physicians, virologists, immunologists, sociologists, epidemiologists, entomologists, and health managers, among others interested in this field, along with many professors from several prestigious national and international institutions, may have the opportunity to debate on the most relevant and updated aspects of this disease and its control.

TOPICS OF THE COURSE
Through theoretical and practical sessions, the main aspects related to dengue will be covered: dengue epidemiology, clinical management, diagnosis, virology and immunology, vector control, environmental risk factors and community participation. Important aspects to be discussed are trends of dengue at global level, impact of climate change, new dengue clinical classification, opportunities for diagnosis, impact of virus diversity, immunogenetics, complexity of dengue immunity and pathogenesis, dengue vaccines, integrated surveillance and control, difficulties, options, challenges, economic burden, new options for control, insecticide resistance, the environment, health systems and dengue, among others. Within the framework of the course, the new global initiatives for dengue and the experiences of several countries and geographical regions will be updated.

In the first week, general lectures as well as round tables and symposia on the topics of clinic, emergency response, diagnostic, pathogenesis, vaccines, antiviral drugs, integrated control and emergent arboviruses are also scheduled. Two mini-courses on GIS and dengue and Modeling of transmission and prediction of dengue as well as other activities and meetings will be also organized .

General topics to be covered

Global epidemiological situation.
International initiatives
Integrated dengue surveillance
Viral genome and structure
Viral replication.
Clinical picture and pathology. Clinical management
WHO dengue clinical classification.
PAHO/WHO Dengue Guidelines for clinical management
Dengue diagnostic and laboratory surveillance
Humoral and cellular immune response. Innate immunity
Antibody dependent enhancement (ADE).
Genetic host factors
Pathogenesis and physiopathology
Animal models
Vaccine candidates and antivirals
Vector ecology
Vector dynamic for dengue transmission
Entomological surveillance.
Chemical and biological vector control methods.
Mechanisms of Insecticide Resistance
Social aspects in dengue
Mathematical models for dengue transmission study
Integral Strategy (EGI) for dengue prevention and control
Ecobiosystem approach for dengue control and prevention
The community role in dengue control.
Cost/effectivity of dengue control activities
Emergency management for outbreak control
Cuban experience: surveillance and control
Climate change and dengue
Emergent arboviruses

OTHERS ACTIVITIES
Three courses on GIS and dengue, Modelling of transmission and prediction of dengue as well as Good Laboratory Practices (GLP) as well as two expert meetings to analyze the main results of the application of the new dengue clinical classification system in the American region (PAHO-IPK) and research priorities (IPK-ITM).

INFORMATION OF INTEREST
ESCMID provides a number of attendance grants for ESCMID young scientists members. Visit ESCMID courses web site for further information.

IVR/WHO provides a number of attendance grants for young scientists. Applicants should submit the registration form of the course to coordinator (see below).

ORGANIZATION OF THE COURSE
The Course is structured in two sections: theoretical and practical. The theoretical section will be conducted during the first week and the practical section during the second week. In the theoretical section, general lectures, round tables and symposia have been scheduled. In the practical section, participants will gather in four groups, according to their interests: clinical care, entomology, community participation/epidemiology and virology/immunology.

Poster session: Participants will have an opportunity to present their results in a poster session scheduled in the first week. Poster characteristics: 94cm wide X 140cm high (vertical position). Deadline for abstract submission: July 1st, 2013.

PROFESSORS CONFIRMED

Luke Alphey, Oxitec
Angel Alvarez, OPS/OMS
Katie Anders, Oxford University Clinical Research Unit, Vietnam
Tamara Awerbuch, University of Harvard, USA
Roberto Barreras, CDC, Puerto Rico
Bruno Canard, CNRS, Marsella
Michael Carr, National Virus Reference Laboratory, Ireland
Margarita Cortés, Sanofi Pasteur
Luiz Jacintho Da Silva, DVI
Delia Enria, Instituto J. A. Maiztegui, Argentina
Carlos Espinal, Sanofi Pasteur
William Hall, National Virus Reference laboratory, Ireland
Scott B. Halstead, DVI
Eva Harris, University of California, Berkeley, USA
Joachim Hombach, IVR, OMS
Olaf Horstick, University of Heidelberg, Germany
Axel Kroeger, TDR/OMS
Louis Lambrechts, Instituto Pasteur, Francia
Pierre Lefevre, Institute of Tropical Medicine, Antwerp, Belgium
Oscar de Leon, Universidad del Valle, Guatemala
Linda Lloyd, San Diego, California, EEUU
Juthathip Mongkolsapaya, Imperial College, UK
Amy Morrison, University of California Davis, California, USA
Jorge Munoz, CDC, Puerto Rico
Ricardo Lourenco de Oliveira, Instituto Oswaldo Cruz, Brasil
Jorge Osorio, University of Wisconsin, USA
Richard Paul, Instituto Pasteur, Francia
Ernesto Pleites, Hospital Benjamín Bloom, El Salvador
Silvia Ranzinger, TDR/OMS
Paul Reiter, Instituto Pasteur, Francia
Bertha Nelly Restrepo, Instituto Colombiano de Medicina Tropical, Colombia
Felix Rey, Instituto Pasteur, Francia
Nidia Rizzo, Universidad del Valle, Guatemala
Anavaj Sakuntabhai, Instituto Pasteur, Francia
David Severson, University of Notre Dame, USA
Donald Shepard, Brandeis University, USA
Patrick Van Der Stuyft, Institute of Tropical Medicine, Antwerp, Belgium
Veerle Vanlerberghe, Institute of Tropical Medicine, Antwerp, Belgium
Pedro Vasconcelos, Instituto Evandro Chagas, Brasil
Nikos Vasilakis, University of Texas Medical Branch, USA
Raman Velayudhan, WHO, Suiza
Marco Vignuzzi, Instituto Pasteur, Francia
Dawn Michel Wesson, University of Tulane, USA
Jamie Whitehorn, London School of Hygiene and Tropical Medicine, Oxford Clinical Research Unit
Andre Yebakima, Mosquito Control Center, Martinique

Cubans
María G. Guzmán, Eric Martínez, Susana Vázquez, María E. Toledo, Juan Bisset, Delfina Rosario, Virginia Capó, Mayling Alvarez, Rosmari Rodríguez-Roche, Ana B. Pérez, Beatriz Sierra, Gisel García, Liset Sánchez, Daniel González, Omar Fuentes, Magdalena Rodríguez, Alberto Baly, Maria del C. Marquetti, Dennys Pérez, Miriam Concepción Rojas, Ana M. Ibarra, Osvaldo Castro, Pedro Más, Ileana Morales, Pedro Ruffin, among other prestigious professors and collaborators (IPK, INHEM, Ministry of Health, Cuba).

OFFICIAL LANGUAGES
The official languages of the Course are: Spanish and English.

REGISTRATION: Theoretical and Practical Sessions = $ 800.00 CUC
Includes registration to both theoretical and practical sections, course materials, welcome cocktail and farewell dinner.
Participants will have the possibility of attending the theoretical or the practical section only or both.

Registration fee for the theoretical section: 12-16, August, 2011 = $ 500.00 CUC.
Registration fee for practical section: 19-23, August, 2011 = $ 400.00 CUC

Registration deadline: 20 July 2013.
Registration form: Download here.

ACCOMMODATION
For hotel room reservation at Palco Hotel, contact Mrs. Mary Elena Segura Teléfono: 53 7 2047235 ext 119 ó al 53 7 2083679 Email: corporativo@hpalco.palco.cu

Also contact, Mrs. María de Lourdes Pérez: Especialista de Reservas. Teléfono: 537 2047235 ext 152 Email: reserva@hpalco.palco.cu

PALCO HOTEL **** (STANDARD ROOM)

Optional services per person
Lunch 14.00 cuc
Dinner 14.00 cuc
One liquid, 1.00 CUC

For hotel room reservation at Mariposa Hotel, contact by Phone: 53-7-2046131 & 2049137. E mail: comercio@maripos.cha.tur.cu

MARIPOSA HOTEL**

Optional services per person
Lunch 8.00 cuc
Dinner 8.00 cuc

CONTACT
Prof. María G. Guzmán, MD, PhD.
Head of the Virology Department.
“Pedro Kourí” Tropical Medicine Institute (IPK).
Director of the WHO/PAHO Center for the Study of Dengue and its Vector.
Phone: (537) 202-0450
Fax: (537) 204-6051